Laziness
Title: Laziness
Category: Science & Technology
Details: Words: 2004 | Pages: 8.5 (approximately 235 words/page)
Laziness
why are we so lazy?
Keratinization, absence of granular layer, and depositation of antibodies
and complement components in the stratum corneum. Most notable is the
hyperproliferation of keratinocytes in the epidermis. These keratinocytes
exhibit an increased mitotic rate and have ten times the turnover rate of
normal keratinocytes. There is also an infiltration of CD4+ T lymphocytes,
monocytes and neutrophils into the epidermis. Recently there has been much
debate over whether psoriasis is mediated by …showed first 75 words of 2004 total…
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…showed last 75 words of 2004 total…is
causing an autoimmune reaction. This antigen may be only expressed during
adolescence, hence the onset of disease during this time. It could be that
these sufferers have lost tolerance to this self antigen and have
initiated an autoimmune response to the new challenge. There may be other
genetic defects which can lead to the psoriatic phenotype, but these are
probably distinct from Type I psoriasis, which I believe to be a true
autoimmune disease.
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